Effect of pneumatization degree of temporal bone air cell on vascular pulsatile tinnitus
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摘要: 为了研究颞骨蜂房气化程度与血管性耳鸣之间的生物力学关系,本文基于典型的血管性耳鸣患者的数据进行了计算分析。首先,基于血管性耳鸣患者CT图像分别建立颞骨蜂房的基础气化和过度气化2种气化程度的三维几何模型。然后,将三维几何模型分别导入Hypermesh软件中并以四面体单元进行网格划分,生成可计算的三维有限元(FE)模型。再将三维有限元模型导入Virtual.Lab Acoustics软件中,加载相同速度边界条件,计算模型的声压幅值响应。最后,以前庭处检测的声压幅值作为计算结果。由2个模型生物力学数值模拟计算的结果,可以发现频率为250 Hz时经气化模型产生的声压幅值比基础模型的值低3.02 dB。经过气化模型产生的声压幅值小于基础模型,且在相同频率下2个模型间的声压幅值差异可被血管性耳鸣患者察觉。这一结论可以尝试为临床创新治疗血管性耳鸣提供新的理论依据。Abstract: To quantify the biomechanic relationship between the degree of pneumatization in the temporal bone air cell and vascular pulsatile tinnitus, the numerical simulation upon a typical vascular pulsatile tinnitus patient's data were conducted in this study. First, the two 3D geometric models of temporal bone air cell, including the basic model and the over-pneumatization model, were developed based on the same patient's CT images individually. Second, the models were meshed with tetrahedral elements by Hypermesh, and computed 3D finite element (FE) models were generated. Then two FE models were imported into Virtual. Lab Acoustics. Third, the same velocity boundary condition was loaded, and then the sound intensity of vibration response was achieved by Virtual. Lab Acoustics. Finally, the sound intensity amplitude at the vestibule was computed. A comparative analysis of two models was done based on the biomechanical numerical simulations. It was shown that the sound intensity amplitude of the over-pneumatization model was 3.02 dB lower than the basic one at 250 Hz. It was found that the difference of amplitude between two models could be perceived by vascular pulsatile tinnitus patient under the condition of same frequency. These would provide a new theoretical basis for innovative treatment of vascular pulsatile tinnitus.
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Key words:
- vascular pulsatile tinnitus /
- sigmoid sinus /
- temporal bone air cell /
- pneumatization degree /
- effect
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[1] 杨东,周慧芳. 耳鸣的发病率与病因分析[J].中国医药科学,2014,4(11):39-42. YANG D,ZHOU H F.Incidence and etiological analysis of tinnitus[J].China Medical Science,2014,4(11):39-42(in Chinese). [2] XENELLIS J, NIKOLOPOULOS T P,FELEKIS D,et al.Pulsatile tinnitus:A review of the literature and an unusual case of iatrogenic pneumocephalus causing pulsatile tinnitus[J].Otology & Neurotology,2005,26(6):1149-1151. [3] 李华,李云英. 古代中医对耳鸣、耳聋的认识[J].吉林中医药,2004,23(12):1-3. LI H,LI Y Y.Cognization of tinnitus,deafness in ancient Chinese medicine[J].Jilin Journal of Traditional Chinese Medicine,2004,23(12):1-3(in Chinese). [4] 王永华,甘雨, 丁水耿.耳鸣的虚实辨证及声学特征分析[J].中国中西医结合耳鼻咽喉科杂志,1996,4(3):129. WANG Y H,GAN Y,DING S G.Deficiency and excess of tinnitus syndrome and analysis of acoustic characteristics[J].Chinese Journal of Otorhinolaryngology of Integrated Traditional and Western Medicine,1996,4(3):129(in Chinese). [5] WANG G P, ZENG R,LIU Z H,et al.Clinical characteristics of pulsatile tinnitus caused by sigmoid sinus diverticulum and wall dehiscence:A study of 54 patients[J].Acta Oto-Laryngologica,2014,134(7):7-13. [6] XUE J,LI T, SUN X,et al.Focal defect of mastoid bone shell in the region of the transverse-sigmoid junction:A new cause of pulsatile tinnitus[J].The Journal of Laryngology & Otology,2012,126(4):409-413. [7] 李宝民,曹向宇, 刘新峰,等.血管源性搏动耳鸣的介入诊断和治疗研究[J].中华耳科学杂志,2014,12(2):190-197. LI B M,CAO X Y,LIU X F,et al.Diagnosis and interventional therapy of pulsatile tinnitus caused by vascular[J].Chinese Journal of Otology,2014,12(2):190-197(in Chinese). [8] 王涛,谭毅. 搏动性耳鸣的病因检查诊断及治疗[J].中国临床新医学,2012,5(11):1097-1100. WANG T,TAN Y.Pulsatile tinnitus:Etiology,assessment and treatment[J].Chinese Journal of New Clinical Medicine,2012,5(11):1097-1100(in Chinese). [9] GOLOGORSKY Y, MEYER S A,POST A F,et al.Novel surgical treatment of a transverse-sigmoid sinus aneurysm presenting as pulsatile tinnitus:Technical case report[J].Neurosurgery,2009,64(2):393-394. [10] EISENMAN D J. Sinus wall reconstruction for sigmoid sinus diverticulum and dehiscence:A standardized surgical procedure for a range of radiographic findings[J].Otology & Neurotology,2011,32(7):1116-1119. [11] TOPAL O, ERBEK S S,ERBEK S.Subjective pulsatile tinnitus associated with extensive pneumatization of temporal bone[J].European Archives of Oto-Rhino-Laryngology,2008,265(1):123-125. [12] TVZ M,DO RU H, YESILDAG A.Subjective pulsatile tinnitus associated with extensive pneumatization of temporal bone[J].Auris Nasus Larynx,2003,30(2):183-185. [13] TIAN S,MAO R, LIU Z H,et al.The relationship of coloboma of cortical plate attaching sigmoid sinus and vascular pulsatile tinnitus:A numerical study[C]//IFMBE Proceedings.Berlin:Springer International Publishing,2015,47:72-75. [14] 李增刚,詹福良. 声学仿真计算高级应用实例[M].北京:国防工业出版社,2014:3-4. LI Z G,ZHAN F L.Senior application examples of acoustic simulation compution[M].Beijing:National Defense Industry Press,2014:3-4(in Chinese). [15] BRITTON B H, 薛君武.压力变化所致的前庭反应[J].国外医学:耳鼻咽喉科学分册,1987(4):216-218. BRITTON B H,XUE J W.Vestibular response caused by pressure change[J].Foreign Medical Sciences:Section of Otolray Ngology Foreign Medical,1987(4):216-218(in Chinese). [16] 杜功焕,朱哲民, 龚秀芬.声学基础[M].3版.南京:南京大学出版社,2012:108-127. DU G H,ZHU Z M,GONG X F.Fundamentals of acoustics[M].3rd ed.Nanjing:Nanjing University Press,2012:108-127(in Chinese). [17] 詹福良,徐俊伟. Virtual.Lab Acoustics声学仿真计算从入门到精通[M].西安:西北工业大学出版社,2013:16-17. ZHAN F L,XU J W.Virtual.Lab Acoustics,acoustic simulation from entry to master[M].Xi'an:Northwestern Polytechnical University Press,2013:16-17(in Chinese). [18] 罗维之,梁之安. 人听觉辨别阈和听阈的加龄变化[J].声学学报,1998,23(2):157-162. LUO W Z,LIANG Z A.Auditory discrimination threshold and changes in auditory discrimination threshold as people get older[J].Acta Acustica,1998,23(2):157-162(in Chinese). [19] HAN S J, SONG M H,KIM J,et al.Classification of temporal bone pneumatization based on sigmoid sinus using computed tomography[J].Clinical Radiology,2007,62(11):1110-1118. [20] 刘兆会,王振常, 龚树生,等.乙状窦源性耳鸣颞骨气化程度的CT研究[J].中国耳鼻咽喉头颈外科,2011,18(4):171-173. LIU Z H,WANG Z C,GONG S S,et al.CT study of pneumatization of the temporal bone in cases with pulsatile tinnitus caused by sigmoid sinus abnormalities[J].Chinese Archives of Otolaryngology-Head and Neck Surgery,2011,18(4):171-173(in Chinese). [21] OTTO K J, HUDGINS P A,ABDELKAFY W,et al.Sigmoid sinus diverticulum:A new surgical approach to the correction of pulsatile tinnitus[J].Otology & Neurotology,2007,28(1):48-53. [22] AIKOYE A A, TANG T Y,MEYER F J.Local anaesthetic surgical treatment of severe objective pulsatile tinnitus:A useful technique[J].Annals of the Royal College of Surgeons of England,2012,94(4):139-140.
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