Abstract: An integrated guidance and control (IGC) algorithm for a class of missile with networked packet dropouts was researched. Considering that a number of ground-based radars were used to observe on the target simultaneously and the target information was shared with the missile through the network. Networked packet dropouts were described as the communication topology model between the missile and radars. The pitch channel IGC model including three cascaded subsystems was established. In this way, virtual controllers were designed for each subsystem. To guarantee the stability of the missile when packets dropouts occur, the corresponding filters were designed for the virtual controllers. An IGC algorithm was put forward by adopting sliding-mode control and back stepping control method. Sufficient condition to guarantee the bounded-input bounded-output (BIBO) stability of the system was simultaneously derived. Finally, simulation results demonstrate the effectiveness of the proposed method.