The effective technique approach to realize the air combat by use of long-range air-to-air missiles was studied. The communication net, which is used to get movement information of long-range targets and transmit the missile’s guidance command information, was composed of various detecting and communication means available. The net, missile carrier and the missile form the combat system that carries out attacking the long-range targets. The project of the long-range air-to-air missiles combat system was proposed. The relative mathematic model of each component was established. The influence of errors induced by information detection, transmission, fusing on combat effect was analyzed. The simulation of the combat system is completed. The results show that the project of long-range air-to-air missiles combat system is effective.