Abstract: Interpersonal citizenship behavior, an important part of organizational citizenship behavior, refers to some mutual actions between coworkers. Studies have found that factors such as coworker relationship and network centricity all have an impact on interpersonal citizenship behavior. The main purpose of the present article is to discuss the relationship among employee mindfulness, coworker trust, interpersonal citizenship behavior and task interdependence. We developed and tested a structural model to analyze 342 valid questionnaire. The main findings are as follows. Firstly, mindfulness has significant positive impact on coworker trust. Secondly, mindfulness can affect interpersonal citizenship behavior both directly and indirectly, which means trust plays a partial meditation role between the two variables. Besides, linear-regression analysis indicates that task interdependence can moderate the relationship between trust and interpersonal citizenship behavior.