Abstract: The current market status is experiencing a shift from the fundamental role to the decisive one. At this stage, economic monopoly which has appeared in the process of capitalist development will arise. Different from administrative monopoly, economic monopoly is conducive to the development of productive forces at a specific stage. The monopoly appeared in the capitalism development was generally implemented in the form of business organization while the current economic monopoly arises in the form of industrial cluster, which is not subject to antitrust restrictions. Some industrial clusters in China have gained a dominant position in the share of the market, which enables them to achieve economic monopoly. To accomplish economic monopoly, the industrial clusters need the guide of leading enterprises and sharpen the competitive edge both externally and internally.