Abstract: In order to cultivate innovative and complex talents with innovative spirit and practical ability, the "artificial intelligence+engineering practice" concept was introduced into the comprehensive innovation training curriculum based on the "Innovation Action Plan of Artificial Intelligence in Colleges and Universities". Artificial intelligence teaching and training was involved in the course, and the curriculum framework with the new concept was established. Two artificial intelligence innovation projects have been finished through the course. One was the "drilling operating platform based on virtual reality technology", the other was "intelligent flower watering robot based on image recognition". The project of "artificial intelligence + engineering practice" has promoted the quality of the curriculum itself, enhanced the communication between the teachers, developed the construction of the teaching team, stimulated the students' enthusiasm for learning, and cultivated the students' creative and cooperative ability. The project of "artificial intelligence + engineering practice" is of great significance to the development of the curriculum.