Abstract: As John Updike's masterpiece, the Rabbit Tetralogy are of rich artistic and humanistic value, and broadening its critical perspective is of positive significance. Using the methods of cultural criticism and ethical literary criticism, the Rabbit Tetralogy are studied to explore the changing reality of American society depicted by John Updike and the resulting twists and confusions in national life, and analyze the ethical relationship depicted in the novels and the way it is narrated. Readers have discovered that the Rabbit Tetralogy provide a window into the transition of contemporary American social values, and inspired people to think and discuss ways to solve realistic problems. Through his criticism of American reality and culture, John Updike realized the isomorphism of literature and reality, through his unique narrative style and technique, John Updike realized the interaction between narration and ethics, and established the dimension of literary narrative ethics.