Abstract: This paper mainly adopts the method of literature research to study Mao Zedong's thought on political construction, and explore the logic and starting point of the thought on political construction of the Communist Party of China(CPC). Mao Zedong attached great importance to strengthening the Party's construction politically, and his thought was influenced by the Marxist thought that the party should have its own political stand and political attribute, and should form the core of leadership. The specific contents are as follows: attaching importance to "politicizing intraparty life", improving the level of intraparty politics, "the Party leads everything", maintaining the authority of the CPC Central Committee, maintaining the correct political direction, and attaching importance to the important role of the Party cadres.