Abstract: In public crises, how to accurately and effectively communicate scientific information to the public is an important issue in the field of science communication. Taking the widely concerned L’Aquila incident as an example, the paper carries out the text analysis to sort out the relevant materials and academic comments on the L’Aquila incident, and reflects on how scientists can communicate scientific information to the public and help the public make sound decisions in public crises. After clarifying the context of the L’Aquila incident, the paper points out that science communication activities in public crises are facing three challenges, namely, communicating science with uncertainty to the public, the conflicting roles of scientists in public crises, and the competition between non-scientific and scientific knowledge. In addition, based on the idea of “science for the people”, the paper discusses how to deal with the challenges of science communication in public crises. Finally, the paper proposes that “plural” science and “two-way” science should be communicated from the perspectives of “what science to communicate” and “how can science be communicated”.