Abstract: The generation and development of the low-altitude economy has an intrinsic logical connection with Marx's spatial thought and contains a profound theoretical foundation of Marx’s spatial thought. Marx believed that space is the element needed for all production and all human activities, and is inevitably linked to economic development and capital drive. Based on Marx’s spatial thought, low-altitude economy, as a new expansion of human beings in the spatial dimension, is a typical representative of the new quality of productive forces, and has a positive impact on the construction of a better life. Of course, while the low-altitude economy has demonstrated its vitality, it also carries certain ethical risks. With an eye to the future, and driven by capital, it is necessary to clearly understand and grasp the inherent laws and real-life contradictions in the development of low-altitude economy, take into account the developmental effectiveness of low-altitude economy and ethical justice, and promote the sustainable development of low-altitude economy from the perspective of synergistic development of spatial production and spatial fairness, balanced consideration between economic gain and spatial fairness, harmonization of the subject’s nature and the rights and interests of the spatial structure, and the two-pronged approach of sustained development and spatial protection.