Abstract: One Hundered Years of Solitude is the masterpiece of Garcia Marquez, the representative of Contemporary Columbia Literature. This essay uses Plato's allegory of the cave to analyze the sense of solitude which permeated this novel. It reaches the conclusion that the solitude of the protagonists in the work reveals the inconsistency between desire for truth and reality, and the conflict between development of reason and religious belief. It points out that in order to cast off the shadow of solitude, Latin American people should step out of the dark cave and get rid of their fatuity and conformism with the help of love and solidarity.