Abstract: The college students are the bright future of our motherland, the tremendous hope of our nation, and the shining small sun of the family. They have to shoulder the great responsibility of the construction and take-off of our country. How to innovate college career planning and tutoring system and combine the school education objectives with student-s personal development goals These are the urgent problems of advanced education. Considering the after effect and passivity of college career, this article, from a view of the overall situation, combines the multi-objective decision-making with BP artificial neural network appropriately, and constructs the general diathesis estimation model for university students. Not only does the research enrich the theoretical methods of university career planning, but also provides an effective implementation tool and instrument for scientific evaluation on career planning.