Abstract: Rural grass-roots anti-corruption work is important for honest government. It is also an important and indispensable part of the construction of a new socialist countryside. The paper made a comprehensive theoretical and empirical analysis on the rural grass-roots anti-corruption practice of Deqing county, Guangdong Province. The County continuously improves the effectiveness of its legal education by clarifying its aim and purpose. It closely integrates the legal education and professional ethics, social ethics and family values education. It focuses on people-s democracy, respect for the pioneering spirit, and the improvement of the anti-corruption system. It has built an anti-corruption institutional system in line with the scientific, rational and practical principles. It attaches great importance to the role of the Internet and other means of information technology. It gives supervision to all aspects of the exercise of power. The county has created a good atmosphere, and straightened out the relationship between supervision subject and supervision object, broadened the channels of supervision, and integrated supervision resources to form a combined monitoring force. The county has made great efforts on the evaluation and promotion of cadres to make sure that they are clean. It has improved the evaluation system and reward system, maintained the strong momentum against corruption, and established a punishing mechanism as a warning system so that no one dares to be corrupt.