| Citation: | WANG Qionghua, YUAN Rongying, LIU Chaoet al. Microscopic imaging technology with electrowetting liquid lens[J]. Journal of Beijing University of Aeronautics and Astronautics, 2022, 48(9): 1774-1781. doi: 10.13700/j.bh.1001-5965.2022.0302(in Chinese)
|
The electrowetting liquid lens is increasingly favored by researchers due to its tunable focal length, fast response, convenient operation, and low power consumption. It can solve some technical problems such as mechanical jitter and discrete zoom in microscopic imaging systems, thus promoting the intelligence and lightweight of these systems. Firstly, the basic concept of and the research on electrowetting liquid lenses are described. Then, the latest research on the microscopic imaging technology with the electrowetting liquid lens is reviewed. Two microscopic imaging technologies, continuous optical zoom and axial scanning, are introduced in detail. Finally, the prosects and challenges of the microscopic imaging technology with the electrowetting liquid lens are presented.
| [1] |
HUANG Y, CHEN X, ZHANG H, et al. Design of a high-performance digital slit-lamp microscope with five-switched zoom[J]. Applied Sciences, 2020, 10(8): 2757. doi: 10.3390/app10082757
|
| [2] |
张润泽. 长工作距变焦显微系统物镜设计[D]. 长春: 长春理工大学, 2019: 12-16.
ZHANG R Z. Design of zoom microscope objective with long working distance[D]. Changchun: Changchun University of Science and Technology, 2019: 12-16(in Chinese).
|
| [3] |
阎帅, 向阳, 李琦, 等. 用于细胞发酵罐的长工作距变焦显微系统设计[J]. 长春理工大学学报(自然科学版), 2020, 43(2): 8-13. doi: 10.3969/j.issn.1672-9870.2020.02.002
YAN S, XIANG Y, LI Q, et al. Design oflong working distance zoom microscopy system for cell fermenter[J]. Journal of Changchun University of Science and Technology(Natural Science Edition), 2020, 43(2): 8-13(in Chinese). doi: 10.3969/j.issn.1672-9870.2020.02.002
|
| [4] |
许利峰, 张新, 曲贺盟, 等. 高变倍比连续变焦体视显微镜物镜设计[J]. 应用光学, 2013, 34(1): 38-44. https://www.cnki.com.cn/Article/CJFDTOTAL-YYGX201301009.htm
XU L F, ZHANG X, QU H M, et al. Optical design of high-magnification zoom stereo microscope objective[J]. Journal of Applied Optics, 2013, 34(1): 38-44(in Chinese). https://www.cnki.com.cn/Article/CJFDTOTAL-YYGX201301009.htm
|
| [5] |
王佳楠, 向阳. 变焦电子腹腔镜物镜光学系统的设计[J]. 长春理工大学学报(自然科学版), 2018, 41(1): 67-70. doi: 10.3969/j.issn.1672-9870.2018.01.017
WANG J N, XIANG Y. Design of optical system for zoom electronic laparoscope objective lens[J]. Journal of Changchun University of Science and Technology(Natural Science Edition), 2018, 41(1): 67-70(in Chinese). doi: 10.3969/j.issn.1672-9870.2018.01.017
|
| [6] |
ZONG W, ZHAO J, CHEN X, et al. Large-field high-resolution two-photon digital scanned light-sheet microscopy[J]. Cell Research, 2015, 25(2): 254-257. doi: 10.1038/cr.2014.124
|
| [7] |
宋贤林. 大景深轴向高分辨光声显微成像方法研究[D]. 武汉: 华中科技大学, 2019: 14-29.
SONG X L. Photoacoustic microscopy with high axial resolution in a large depth of field[D]. Wuhan: Huazhong University of Science and Technology, 2019: 14-29(in Chinese).
|
| [8] |
BENSCHOP J, VAN ROSMALEN G. Confocal compact scanning optical microscope based on compact disc technology[J]. Applied Optics, 1991, 30(10): 1179-1184. doi: 10.1364/AO.30.001179
|
| [9] |
DIXON A E, DAMASKINOS SATKINSON M R. Transmission and double-reflection scanning stage confocal microscope[J]. Scanning, 1991, 13(4): 299-306. doi: 10.1002/sca.4950130405
|
| [10] |
GREWE B F, LANGER D, KASPER H, et al. High-speed in vivo calcium imaging reveals neuronal network activity with near-millisecond precision[J]. Nature Methods, 2010, 7(5): 399-405. doi: 10.1038/nmeth.1453
|
| [11] |
SHI R, JIN C, XIE H, et al. Multi-plane, wide-field fluorescent microscopy for biodynamic imaging in vivo[J]. Biomedical Optics Express, 2019, 10(12): 6625-6635. doi: 10.1364/BOE.10.006625
|
| [12] |
王琼华, 刘超, 王迪, 等. 液体光子器件[M]. 北京: 科学出版社, 2021: 76.
WANG Q H, LIU C, WANG D, et al. Liquid photonic device[M]. Beijing: Science Press, 2021: 76(in Chinese).
|
| [13] |
BERGE B, PESEUX J. Variable focal lens controlled by an external voltage: An application of electrowetting[J]. The European Physical Journal E, 2000, 3(2): 159-163. doi: 10.1007/s101890070029
|
| [14] |
KUIPER S, HENDRIKS B H W. Variable-focus liquid lens for miniature cameras[J]. Applied Physics Letters, 2004, 85(7): 1128-1130. doi: 10.1063/1.1779954
|
| [15] |
KOPP D, BRENDER T, ZAPPE H. All-liquid dual-lens optofluidic zoom system[J]. Applied Optics, 2017, 56(13): 3758-3763. doi: 10.1364/AO.56.003758
|
| [16] |
ZHAO P, LI Y, ZAPPE H. Accelerated electrowetting-based tunable fluidic lenses[J]. Optics Express, 2021, 29(10): 15733-15746. doi: 10.1364/OE.423460
|
| [17] |
ERIC S, BRUNO B, FRANCK F, et al. Optical design rules of a camera module with a liquid lens and principle of command for AF and OIS functions[C]//Proceedings of SPIE, 2010, 7849: 784903-1-784903-14.
|
| [18] |
OBER M S, DERMODY D, MAILLARD M, et al. Development of biphasic formulations for use in electrowetting-based liquid lenses with a high refractive index difference[J]. ACS Combinatorial Science, 2018, 20(9): 554-566. doi: 10.1021/acscombsci.8b00042
|
| [19] |
KANG M, YUE R F. Variable-focus liquid lens based on EWOD[J]. Journal of Adhesion Science and Technology, 2012, 26(12-17): 1941-1946. doi: 10.1163/156856111X600479
|
| [20] |
SONG X, ZHANG H X, LI D, et al. Electrowetting lens with large aperture and focal length tunability[J]. Scientific Reports, 2020, 10(1): 16318. doi: 10.1038/s41598-020-73260-4
|
| [21] |
LI L, LIU C, REN H, et al. Annular folded electrowetting liquid lens[J]. Optics Letters, 2015, 40(9): 1968-1971. doi: 10.1364/OL.40.001968
|
| [22] |
WANG J H, ZHOU X, LUO L, et al. Tunable liquid lens integrated with aspheric surface[J]. Optics Communications, 2019, 445: 56-63. doi: 10.1016/j.optcom.2019.03.066
|
| [23] |
XU J, ZHAO Y, LIU C, et al. Non-aqueous organic solution based on a large-aperture spherical electrowetting liquid lens with a wide tunable focal length range[J]. Journal of Materials Chemistry C, 2022, 10(17): 6778-6793. doi: 10.1039/D1TC05823A
|
| [24] |
LI L, WANG D, LIU C, et al. Zoom microscope objective using electrowetting lenses[J]. Optics Express, 2016, 24(3): 2931-2940. doi: 10.1364/OE.24.002931
|
| [25] |
JIANG Z, WANG D, ZHENG Y, et al. Continuous optical zoom microscopy imaging system based on liquid lenses[J]. Optics Express, 2021, 29(13): 20322-20335. doi: 10.1364/OE.432290
|
| [26] |
KUANG F L, YUAN R Y, WANG Q H, et al. Large zooming range adaptive microscope employing tunable objective and eyepiece[J]. Scientific Reports, 2020, 10(1): 14644. doi: 10.1038/s41598-020-71507-8
|
| [27] |
MURALI S, THOMPSON K, ROLLAND J. Three-dimensional adaptive microscopy using embedded liquid lens[J]. Optics Letters, 2009, 34(2): 145-147. doi: 10.1364/OL.34.000145
|
| [28] |
MURALI S, MEEMON P, LEE K S, et al. Assessment of a liquid lens enabled in vivooptical coherence microscope[J]. Applied Optics, 2010, 49(16): 145-156. doi: 10.1364/AO.49.00D145
|
| [29] |
TEHRANI K F, LATCHOUMANE C V, SOUTHERN W M, et al. Five-dimensional two-photon volumetric microscopy of in-vivo dynamic activities using liquid lens remote focusing[J]. Biomedical Optics Express, 2019, 10(7): 3591-3604. doi: 10.1364/BOE.10.003591
|
| [30] |
MA H, CHENG Z, WANG Z, et al. Fast controllable confocal focus photoacoustic microscopy using a synchronous zoom opto-sono objective[J]. Optics Letters, 2019, 44(7): 1880-1883. doi: 10.1364/OL.44.001880
|
| [31] |
LI L, XIAO L, WANG J H, et al. Movable electrowetting optofluidic lens for optical axial scanning in microscopy[J]. Opto-Electronic Advances, 2019, 2(2): 10-14.
|
Figures(8)
Copyright © Journal of Beijing University of Aeronautics and Astronautics
Address: Editorial Department of Journal of Beijing University of Aeronautics and Astronautics, 37 Xueyuan Road, Haidian District, Beijing Post Code: 100191 Email: jbuaa@buaa.edu.cn
Supported by:
Beijing Renhe Information Technology Co., Ltd.
DownLoad:
