| Citation: | LI C Q，ZHAN Y Q，WANG Z M，et al. Numerical simulation of iliac vein compression syndrome in hemodynamics[J]. Journal of Beijing University of Aeronautics and Astronautics，2024，50（8）：2646-2654 （in Chinese） doi: 10.13700/j.bh.1001-5965.2022.0693
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To investigate the reasons for the typical symptoms of iliac vein compression syndrome with the collateral veins, a typical iliac vein blood flow field with a collateral vein was numerically studied. The viscous resistance coefficient of the porous media model was adjusted to simulate the second and third development stages of iliac vein compression syndrome. The hemodynamic characteristics in the two stages were analyzed and compared, e.g., pressure gradient, blood helicity, and wall shear stress. The results show that the pressure gradient between the left iliac vein and the inferior vena cava is 107 Pa in the third stage, which is far greater than 31 Pa in the second stage but less than the criterion of iliac vein compression syndrome, i.e., 266 Pa. In the third stage, the left iliac vein is replaced by the collateral vein to realize the venous blood flow. When the blood flow pathway changes, the blood helicity and wall shear stress in the collateral vein and right iliac vein are much greater than those in the second stage. The obstruction of the left iliac vein changes the transport pathway of the erythrocyte and prolongs the transport time. Although the venous blood flow in iliac vein compression syndrome with the collateral vein is normal, the patient still presents the typical symptoms due to the combined effort of the excessive pressure gradient, large blood helicity, abnormal wall shear stress, and transport hysteresis of erythrocytes.
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