A simulation method based on programmable graphic processing unit (GPU) was proposed to simulate charge coupled device (CCD) vidicon image processing. The flow-operating mode and parallel computation ability of GPU were utilized to process each pixel, including Gamma correction, brightness and contrast adjustment, color-temperature adjustment, and color-saturation processing. The principle of Gamma correction and the necessity to implement it before other operations were analyzed. The relation between luminance and pixel color was discussed. A method to compute luma signal of current image was proposed. The luma scale was defined and image processing was based on it. A method to simulate the dynamic noise in low luminance condition was introduced. The results show that this method can simulate the imaging effect of real CCD vidicon in complex illumination environment with high speed and efficiency which are required in real-time simulation.