Abstract: The applying of the ventilation stress in the reliability test of the airborne electronic equipment were introduced. Combined with the GJB and the characteristic of the environment control system of airplane, the ventilation and cooling condition of airborne electronic equipments in factual use environment was investigated;Combined with the life profile, task profile and its environment condition, flight altitude, flight mach number, etc, the stress in reliability test and the problems in those standards in use present were investigated. The simulation of the ventilation and cooling conditions of factual environment was introduced. A ventilation and cooling profile with reason in reliability testing (including the conforming method of parameters of ventilate air—such as flux, temperature, humidity and cleanness etc) was established. Through research of a product with these items, the ventilation cooling profile (including the parameters of ventilate air and infliction time )which was compatible with the temperature profile was given.