Abstract: It is presented here that the idea on comprehensive application of System Engineering and Quality Function Deployment. A standardizing and programmable method is developed for determining requirements, making trade-off and finally, implementing these requirements, by means of System Engineering's fundamentals and process, and the frame of Quality Function Deployment. According to the process of practical work, the aim of "Customer the First" is reflected throughout the process, i. e. customer requirements basically drive the decision-making of the top policy-making team, determine the development and production of products. It provides scientific and measurable methods for decisions of the top-down managers by introducing the fundamentals and process of System Engineering to Quality Function Deployment. It is mainly introduced that the process and methods for the comprehensive trade-off of alternatives.