Abstract: To solve the requirement problem of modern industrial control system to wireless communication technology, the bluetooth protocol was analysed and the integration and development of bluetooth wireless communication technique in industrial device control were introduced, which included accessing the bluetooth chip by UART (universal asynchronous receiver/transmitter) of using HCI(host controller interface) command packets, event packets and data packets. The two steps of establishing bluetooth wireless net are necessary: the master finds slave and the connecting between master and slave is established. A remote operating panel of numerical control machine tool based on bluetooth was designed, the cable was replaced by bluetooth, which included the system function, such as automatic connection, mode selection and over-time alarm. The format of data packet by using wireless communication was designed, and the encode and decode of electro-handwheel pulse were analysed.