Abstract: In order to satisfy the need of rapid development of modern airplane design,the development process of expert system is presented for airplane structure durability design and analysis with Visual C+ + language. This expert system includes knowledge base formed by organizing existed expert's knowledge and expert's experience, experiment database on the basis of many kinds of material experiment, and calculation model formed by calculation manner of original design and analysis. This expert system realizes the normalization of durability design and analysis, and is applied in certain model airplane durability evaluation. This paper presents the system organization structure, its functions and also shows an example and gives the conclusion.