Influence of forward acceleration on hemodynamic characteristics of carotid arteries:A numerical simulation
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摘要:
人们在日常或某些特殊条件下常会面临方向和大小发生迅速变化的加速度环境，已有研究发现加速度环境会影响心血管系统生理、病理特征。利用计算机模拟方法详细研究了向前加速度环境下人体颈动脉内的血流动力学参数变化规律。结果表明：加速度会对颈动脉内压力、压力梯度、壁面剪切应力等与血管生理、病理现象密切相关的血流动力学参数产生显著影响。研究结果为加速度环境下颈动脉生理、病理研究提供了一定的理论依据，也为航空航天领域加速度环境下人员防护提供参考。
Abstract:Humans are usually subjected to acceleration with fast changing directions and magnitude in ordinary or some special situations. Previous studies have found that acceleration had physiological and path-ological influence on cardiovascular system. However, more in-depth investigations need to be done at present. In this study, the computer simulation method was used to study the hemodynamic parameter variation features laws of carotid artery under forward acceleration condition. The results reveal that acceleration has significant influence on the hemodynamic parameters including pressure, pressure gradient, wall shear stress, etc. in carotid artery, which have close relationship with physiological and pathological behavior of artery. This study provides theoretical basis for the research of carotid artery physiology and pathology under acceleration conditions, and also gives reference for human protection under acceleration conditions in aeronautic and astronautic fields.
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Key words:
- acceleration /
- carotid artery /
- hemodynamic characteristics /
- blood flow rate /
- pressure gradient
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图 3 颈动脉模型壁面压力梯度分布云图
Figure 3. Contours of wall pressure gradient distribution of carotid artery model
图 5 颈动脉模型壁面剪切应力分布云图
Figure 5. Contours of wall shear stress distribution of carotid artery model
图 7 颈动脉分叉处4个分区上平均压力和压力梯度变化曲线
Figure 7. Average pressure and pressure gradient curves of four areas at carotid branch
表 1 T1~T8代表的具体时刻(记录周期初始时刻为T = 0)
Table 1. Specific time represented by T1-T8 (beginning of cycle is defined as T = 0)
时间点 T1 T2 T3 T4 T5 T6 T7 T8 时间/s 0.05 0.1 0.15 0.7 1.05 1.1 1.15 1.7 
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